The Sage Group

Critical Limb Ischemia Volume I, U.S. Epidemiology, 2016 Supplement

Research on the epidemiology of critical limb ischemia (CLI) remains sparse. Since the 2010 publication of Critical Limb Ischemia Volume I, two U.S. epidemiological studies have been published. In addition, a meta-analysis of four Western European and two Asian studies included prevalence data.

This new, population-based prevalence data is employed to calculate the prevalence of CLI for 2015-2030. These prevalence estimates are assessed and compared with THE SAGE GROUP’S 2010 and 2016 estimates based on the Diabetes Method.

The current research also includes updated peripheral artery disease prevalence estimates for the 2015-2030 period. This reflects the increased prevalence of diabetes since the 2010 publication.

Diabetes Method PAD estimates for 1995 and the 2010-2030 period are compared with estimates based on two other studies. The percent prevalence in one of these was the basis for most commonly-quoted PAD estimate of 8-12 million, while the other is a more recent epidemiology study of PAD and CLI prevalence and incidence.

Incidence estimates for both peripheral artery disease and critical limb ischemia are included for 2015-2030.

Prevalence is defined as the number of new and old cases of critical limb ischemia and peripheral artery disease. Incidence is defined as the annual number of new cases of these diseases.

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